White spot lesions (WSL) that occur on teeth after orthodontic appliances have been attached are caused by bacterial demineralization of the enamel surface.This study investigated the anti-demineralization effect of orthodontic resins containing mesoporous bioactive glass nanoparticles (MBN) doped with gallium, which has antibacterial activity, as
Autophagy is a catabolic Cutters - Nail Cutters self-degradative pathway that promotes the degradation and recycling of intracellular material through the lysosomal compartment.Although first believed to function in conditions of nutritional stress, autophagy is emerging as a critical cellular pathway, involved in a variety of physiological and pat
Oxygen is essential to all the aerobic organisms.However, during normal development, disease Place Mat and homeostasis, organisms are often challenged by hypoxia (oxygen deprivation).Hypoxia-inducible transcription factors (HIFs) are master regulators of hypoxia response and are evolutionarily conserved in metazoans.The homolog of HIF in the geneti
Metastatic clear cell renal cell carcinoma (mccRCC) benefits from several treatment options in the first-line setting with VEGFR inhibitors and/or immunotherapy including anti-PD-L1 or anti-PD1 agents.Identification of predictive biomarkers is highly needed to optimize patient care.Circulating markers could reflect the biology of metastatic disease
Tylosema esculentum (marama bean) is an important orphan legume from southern Africa that has long been considered to have the potential to be domesticated as a crop.The chloroplast genomes of 84 marama samples collected from various geographical locations in Namibia and Pretoria were compared in this study.The cp genomes were analyzed for diversit